Arsenic
A [HD]
DILI Likelihood
Score A [HD] — Well-Known Hepatotoxin (at high doses)
This drug is well known, well described, and well reported to cause either direct or idiosyncratic liver injury, with a characteristic signature.
More than 50 cases including case series have been described in the medical literature.
[HD] High dose only — Liver injury occurs at high doses (e.g. overdose). Risk is lower at normal therapeutic doses.
Classification