Buprenorphine
Brand name: Buprenex
B[HD]
DILI Likelihood
Score B[HD] — Known Hepatotoxin (at high doses)
This drug is known or highly likely to cause idiosyncratic liver injury and has a characteristic signature.
Between 12 and 50 cases including small case series have been described in the medical literature.
[HD] High dose only — Liver injury occurs at high doses (e.g. overdose). Risk is lower at normal therapeutic doses.
Classification