Entacapone

Brand name: Comtan

DILI Likelihood

Score D — Possible Hepatotoxin

Single case reports have appeared implicating this drug, but the evidence is limited.

Fewer than 3 cases have been reported in the literature. No characteristic signature has been identified, and the case reports may not have been very convincing.

Scoring guide (A through X) →

Classification

Primary class CNS

Secondary class Parkinson disease

FDA approval 2003

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